EPA, 947 F.2d 1201 . Unfortunately, this ruling leaves many consumer products that can legally contain trace levels of asbestos still. The position of all health authorities is definitely that if asbestos is definitely left undisturbed and its fibers aren’t airborne then it poses little risk. However, once fibers become airborne and are ‘friable’ and can become ingested or inhaled then it is harmful and can lead to asbestos-related diseases such as for example asbestosis and lung malignancy. Why is it so harmful? One theory is due to fiber size.We observed a lower life expectancy risk of cardiovascular system disease among both individuals of African descent and those of European descent. In the African ancestry subgroup, only 2 of 887 patients with cardiovascular system disease carried an NPC1L1 inactivating mutation , in comparison with 13 of 4655 controls , representing a 17 percent decrease in the risk of cardiovascular system disease among carriers . In participants of European ancestry, 9 of 28,223 sufferers with cardiovascular system disease carried the mutation , in comparison with 57 of 77,378 controls , representing a 57 percent decrease in the risk of coronary heart disease among carriers . Debate We sequenced the protein-coding regions of NPC1L1 in 22,092 participants and identified 15 rare mutations that were expected to disrupt the proteins.