Some variations of the viruses carried by deer mice, white-footed mice, rice cotton and rats rats in North America could cause the rare, but deadly disease HPS. It is contracted when people breathe the hantavirus through infected rodent urine and droppings; when people contact infected urine, droppings or nesting materials or through a bite from an infected animal. It is extremely rare to get the disease – because it was recognized in 1993 there have been 60 situations in California and 587 nationally, according to the National Park Service. HPS can lie dormant for one to five weeks. Symptoms begin with fever, severe muscle mass aches and fatigue. A couple of days later the patient shall have a hard time breathing and could experience headaches, dizziness, chills, nausea, vomiting, diarrhea and stomach pain.Patients with a complete lack of kidney function for more than four weeks and end-stage kidney disease completed the diagnostic criteria . Included in the evaluation was any setting of renal-substitute therapy that was prescribed by the going to doctor. New organ failures for cardiovascular, respiratory, coagulation, and liver systems which were not present at baseline were defined by a rating of 3 or more on the Sequential Organ Failure Assessment ,12 which ranges from 0 to 4 for each of six organ systems, including neurologic and renal systems, with higher scores indicating more serious organ dysfunction .