Dr Gray said one way your body protects against autoimmune disease is definitely by forcing most self-reactive immune cells to die throughout their development. ‘If any self-reactive cells manage to reach maturity, your body normally has a second safeguard of switching these harmful cells into an inactive condition potentially, preventing them from causing autoimmune disease,’ he stated. ‘Until now, there’s been debate about how exactly important the death of self-reactive cells is really as a protection against autoimmune illnesses. Our research has determined two molecules that are needed for this process.This finding suggests that dogs might be an improved pet model for type 1 diabetes than rodents, the authors added. Dr. Joel Zonszein is director of the clinical diabetes middle at Montefiore INFIRMARY in NEW YORK. He stated, Although diabetes in the dog resembles type 1 in human beings, they don’t have got the same inflammatory process we observe in type 1 in human beings. In dogs, we hardly understand what triggers it however.