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American and European Of Adult Myogenic Stem Cell Treatment for enlarged heart attack and advanced heart failureBioheart, developed a biotechnology company specializing in the development of innovative cell therapies to areas of damaged muscle tissue during repair work concentrating the patient’s heart and improvement in cardiac function, is expanding its U.S. And European clinical trials of its MyoCell adult myogenic stem cell composition and MyoCath needle injection catheter product candidates. MyoCell is a non-acute, clinical therapy for the treatment of heart damage in patients with class II or class III heart failure. Bioheart believes that its MyoCell therapy has become the potential to be one of the leading non-acute treatment for severe damage to the heart due to their perceived ability, a currently unmet need for more effective and / or not affordable acute therapies for just damage heart. After more than 19 years of development and testing, large clinical trials clinical study Michael Brown, Bioheart Senior Clinical Scientist. which expanded by statistically significant numbers with an additional 450 plus are pleased with the are pleased with the expansion of our therapy and possibly bringing its benefits to more patients are enthusiastic he added. In the United States closed Bioheart entered in the fourth and last group of its dose-ranging study of the phase I clinical trial MYOHEART MYOHEART study in this last cohort of MYOHEART study, patients received a high-dose injection of 675 million cells, 75 and 225 million cell doses tested in previous cohorts compared. Interim analysis of this data the the August 2006 issue of the Journal of Cardiac Failure, and this data is also at the 10th Annual Meeting of the Heart Failure Society of America, in the which September 2006 was presented. Bioheart In October 2006, the proposed protocol for the U.S. Phase II randomized, double-blind, placebo-controlled MYOHEART II clinical study randomized clinical trial to the United States Food and Drug Administration review. This study was designed to enroll up to 450 patients at approximately 40 centers with the intended purpose of confirming the safety and efficacy of our adult myogenic stem cell transplantation in the treatment of heart failure.

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